Cell Dissociation Market size, share, trends and revenue forecast 2028

Cell Dissociation Market

The cell dissociation industry is expected to experience significant growth over the next few years, driven by advances in cell culture technology, the increasing use of stem cells in research and drug discovery, and the development of novel cell-based therapies.

Cell Dissociation Market in terms of revenue was estimated to be worth $0.6 billion in 2023 and is poised to reach $1.4 billion by 2028, growing at a CAGR of 17.8% from 2023 to 2028 according to a new report by MarketsandMarkets™. Key drivers of the cell dissociation market include, growing use of tissue dissociation products in mammalian cell culture and expanding cell therapy production facilities.

The mammalian-based capacity for recombinant proteins grew yearly at 10.8%, whereas recombinant microbial-based capacity grew at 3.0% yearly. As cell culture is an integral part of developing mammalian-based recombinant therapeutics, the uptake of cell dissociation products is expected to increase with it.

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Enzymatic dissociation products accounted for the larger share of the cell dissociation industry in 2022

Based on the product, the cell dissociation market is segmented enzymatic dissociation products, instruments & accessories, and non-enzymatic dissociation products. In 2022, the enzymatic cell dissociation products segment accounted for the highest revenue.

Uptake of cell dissociation enzymes is expected to increase attributed to increasing cell-based research activities.

By tissue type, the connective tissue segment accounted for the largest market share in 2022

Based on the tissue type, the cell dissociation market is segmented into epethilial tissues, connective tissues, and other tissues such as muscles tissues and nervous tissues. The connective tissues is the dominant segment of the cell dissociation market in 2022 and is also expected to grow at the fastest pace through 2023-2028.

In the past few years, extensive research has been performed to achieve a granular understanding of connective tissue structures.

Pharmaceutical and biotechnology companies are the largest end-users of the elastase market

Based on end-users, the cell dissociation market is segmented into research & academic isntitutes, pharmaceutical & biotechnology companies, and other end users. The pharmaceutical and biotechnology companies are the key end users of the cell dissociation market, with highest revenue share in 2022.

Increasing insvestments by pharmaceutical companies to develop stem cell-based therapies is expected to strengthen the adoption of cell dissociation products.

North America dominates the global trypsin cell dissociation industry

The cell dissociation market is segmented into five major regional segments, namely, North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. In 2022, North America accounted for the largest share in the cell dissociation market, which is attributed to increasing investments in the development of novel cell-based therapies.

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Cell Dissociation Industry Dynamics:


  • Increase in recombinant therapeutics sourced from mammalian cells
  • Growing focus on personalized medicine
  • cGMP approvals for new cell therapy production facilities


  • High cost of cell-based research


  • Advancements in non-enzymatic tissue dissociation


  • Limitations associated with dissociated cell culture

Key Market Players:

The cell dissociation market is moderately consolidated in nature with prominent market players such as Merck KGaA (Germany), Danaher Corporation (US), Thermo Fisher Scientific, Inc. (US), Corning Incorporated (US), Becton, Dickinson and Company (US), STEMCELL Technologies (Canada), PromoCell GmbH (Germany), Miltenyi Biotec (Germany), ATCC (US), HiMedia Laboratories (India), PAN-Biotech (Germany), CellSystems GmbH (Germany), AMSBIO (England), Neuromics (US), VitaCyte, LLC.

(US), ALSTEM (US), Biological Industries (Israel), Gemini Bio (US), Innovative Cell Technologies, Inc. (US), Central Drug House (P) Ltd.

(India), Worthington Biochemical Corporation (US), Capricorn Scientific (Germany), Abeomics (US), and Genlantis, Inc. (US).

Recent Developments

  • In 2020, Miltenyi Biotec launched automated and closed adherent cell culture solutions on CliniMACS Prodigy.
  • In 2020, Merck The company expanded its Life Sciences production facilities in Danvers, Massachusetts, and Jaffrey, New Hampshire (US).
  • In 2020, STEMCELL Technologies partnered with CollPlant to secure CollPlant rhCollagen for STEMCELL's use in cell culture applications.
  • In 2021, Danaher (Cytiva) partnered with Diamyd Medical, wherein Diamyd selected Cytiva's FlexFactory platform for making precision medicine type-1 diabetes vaccines.
  • In 2021, Danaher (Cytiva) collaborated with the Government of Telangana (India) to strengthen the biopharma industry in India with new labs.

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Cell Dissociation Market Advantages:

  • Increased Efficiency: Cell dissociation reagents provide a more efficient and reliable method for dissociating cell samples, which can significantly reduce processing time and improve the quality of the results.
  • Higher Yields: Cell dissociation reagents are designed to maximize cell yield, allowing for more effective downstream applications such as flow cytometry and immunological assays.
  • Improved Quality: Cell dissociation reagents help to ensure that cells are undamaged during the isolation process, thereby resulting in higher quality samples.
  • Cost Effective: Cell dissociation reagents provide a cost-effective solution, as they are typically less expensive than traditional methods.
  • Greater Flexibility: Cell dissociation reagents offer greater flexibility in terms of the types of cells that can be isolated, allowing for a wider range of downstream applications.

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